{"id":895,"date":"2019-07-23T12:47:43","date_gmt":"2019-07-23T12:47:43","guid":{"rendered":"https:\/\/www.drrpadmakumar.com\/blog\/?p=895"},"modified":"2024-10-17T05:07:28","modified_gmt":"2024-10-17T05:07:28","slug":"vitamin-d-deficiency-surgeon-perspective","status":"publish","type":"post","link":"https:\/\/www.drrpadmakumar.com\/blog\/vitamin-d-deficiency-surgeon-perspective\/","title":{"rendered":"Vitamin D Deficiency &#8211; Surgeon&#8217;s Perspective"},"content":{"rendered":"\n<p>Vitamin D deficiency in a Surgeon\u2019s perspective is relevant in<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Parathyroid surgery<\/li>\n\n\n\n<li>Bariatric surgery<\/li>\n\n\n\n<li>Gallbladder surgery<\/li>\n\n\n\n<li>Primary hyperthyroidism<\/li>\n<\/ul>\n\n\n\n<p>Author: Dr R Padmakumar et al.<\/p>\n\n\n\n<p><strong>Contents<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><a href=\"#introduction\" data-type=\"internal\" data-id=\"#introduction\">Introduction<\/a><\/li>\n\n\n\n<li><a href=\"#functions\" data-type=\"internal\" data-id=\"#functions\">Functions<\/a><\/li>\n\n\n\n<li><a href=\"#deficiency-causes\" data-type=\"internal\" data-id=\"#deficiency-causes\">Deficiency Causes<\/a><\/li>\n\n\n\n<li><a href=\"#calcium\" data-type=\"internal\" data-id=\"#calcium\">Correlation of calcium level in vitamin D deficiency<\/a><\/li>\n\n\n\n<li><a href=\"#primary-hyperparathyroidism\" data-type=\"internal\" data-id=\"#primary-hyperparathyroidism\">Primary hyperparathyroidism<\/a><\/li>\n\n\n\n<li><a href=\"#obesity\" data-type=\"internal\" data-id=\"#obesity\">Obesity &amp; After Bariatric Surgery<\/a><\/li>\n\n\n\n<li><a href=\"#gallbladder-disease\" data-type=\"internal\" data-id=\"#gallbladder-disease\">Gallbladder Disease &amp; Vitamin D Deficiency<\/a><\/li>\n\n\n\n<li><a href=\"#treatment\" data-type=\"internal\" data-id=\"#treatment\">Treatment<\/a><\/li>\n<\/ol>\n\n\n\n<h2 class=\"wp-block-heading page-header\" id=\"introduction\">Introduction:<\/h2>\n\n\n\n<p>Vitamin D is a fat soluble vitamin and produced by skin (from cholesterol) when exposed to ultraviolet B radiation (\u201csunshine vitamin\u201d) and also obtained from dietary sources, including supplements. Most important components, vitamin D3 (cholecalciferol) comes from fortified foods, animal foods (fish, eggs and liver) and can be made internally when skin is exposed to ultraviolet (uv) radiation from the sun and vitamin D2 (ergocalciferol)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Deficiency: 25 (OH) D levels below 12 ng\/ml<\/li>\n\n\n\n<li>Inadequate: 25 (OH) D levels between 12-20ng\/ml<\/li>\n\n\n\n<li>An adequate: 25 (OH) D levels between 20-50ng\/ml<\/li>\n\n\n\n<li>Excessive: 25 (OH) D levels over 50nglml<\/li>\n<\/ul>\n\n\n\n<p>Excessive intakes of vitamin D can lead to high levels of calcium (hypercalcemia). The symptoms of this are weakness, confusion, constipation, loss of appetite and development of painful calcium deposits. To avoid this, advice to keep the supplement intake below the tolerable upper limits.<\/p>\n\n\n\n<h2 class=\"wp-block-heading page-header\" id=\"functions\">Functions:<\/h2>\n\n\n\n<p>The need for vitamin D goes way beyond preventing and treating rickets. Various researchers have claimed that vitamin D benefits are associated with the following:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Enhancing intestinal absorption of calcium and phosphorus<\/li>\n\n\n\n<li>Prevention of osteoporosis and osteopenia<\/li>\n\n\n\n<li>Allowing proper functioning of parathyroid hormone<\/li>\n\n\n\n<li>Lowering blood pressure in people with hypertension<\/li>\n\n\n\n<li>Lowering incidence and severity of cardiovascular disorders<\/li>\n\n\n\n<li>Decreasing the incidence of type 2 diabetes: research has shown that those with blood vitamin D level over 25ng\/ml had a 43% reduced risk of developing type 2 diabetes compared with those with levels under 14ng\/ml<\/li>\n\n\n\n<li>Decreasing inflammation: research has shown a decrease in levels of C-reactive protein , a marker of inflammation , with increased levels of vitamin D to just below 21ng\/ml<\/li>\n\n\n\n<li>Reducing risk of allergies in children and adolescents<\/li>\n\n\n\n<li>Prevention of dental caries<\/li>\n\n\n\n<li>Prevention and treatment of depression<\/li>\n\n\n\n<li>Possibly helping with erectile dysfunction (ED)<\/li>\n\n\n\n<li>Regulating cholesterol levels in the blood: it has been shown that without adequate sun exposure, vitamin D precursors turn to cholesterol instead of vitamin D<\/li>\n\n\n\n<li>Decreasing mortality rate of certain cancers<\/li>\n\n\n\n<li>Increase immunity<\/li>\n\n\n\n<li>Deficiency in pregnancy may lead to gestational diabetes, pre eclampsia and small infants<\/li>\n<\/ol>\n\n\n\n<h2 class=\"wp-block-heading page-header\" id=\"deficiency-causes\">Deficiency  &#8211; Causes:<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Inadequate sun exposure<\/li>\n\n\n\n<li>Limited oral intake<\/li>\n\n\n\n<li>Impaired intestinal absorption<\/li>\n\n\n\n<li>Primary hyperparathyroidism<\/li>\n\n\n\n<li>After <a href=\"https:\/\/www.drrpadmakumar.com\/blog\/bariatric-surgery\/\">bariatric surgery<\/a><\/li>\n\n\n\n<li>After <a href=\"https:\/\/www.drrpadmakumar.com\/blog\/laparoscopic-cholecystectomy\/\">Gallbladder surgery<\/a><\/li>\n\n\n\n<li>Parathyroid removal\n<ul class=\"wp-block-list\">\n<li>Accidental during thyroid surgery<\/li>\n\n\n\n<li>For parathyroid adenoma or hyperplasia<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" width=\"422\" height=\"317\" data-src=\"https:\/\/www.drrpadmakumar.com\/blog\/wp-content\/uploads\/2019\/07\/vitamin-d-deficiency.jpg\" alt=\"Vitamin D Deficiency\" class=\"wp-image-896 lazyload\" data-srcset=\"https:\/\/www.drrpadmakumar.com\/blog\/wp-content\/uploads\/2019\/07\/vitamin-d-deficiency.jpg 422w, https:\/\/www.drrpadmakumar.com\/blog\/wp-content\/uploads\/2019\/07\/vitamin-d-deficiency-300x225.jpg 300w\" data-sizes=\"(max-width: 422px) 100vw, 422px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 422px; --smush-placeholder-aspect-ratio: 422\/317;\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading page-header\" id=\"calcium\">Correlation of calcium level in vitamin D deficiency<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>If parathyroid function is normal<\/li>\n\n\n\n<li>When primary hyperparathyroidism<\/li>\n<\/ul>\n\n\n\n<p>In vitamin D deficiency due to reduced oral intake or reduced sun exposure ,Vitamin D level and calcium level will be low with normal parathyroid function. Calcium level will be high and vitamin D will be low when primary hyperparathyroidism exists.<\/p>\n\n\n\n<h2 class=\"wp-block-heading page-header\" id=\"primary-hyperparathyroidism\">Primary hyperparathyroidism<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>There is high calcium level in the blood<\/li>\n\n\n\n<li>May present with parathyroid tumor<\/li>\n\n\n\n<li>High PTH takes calcium from the bone and shut down calcium absorption<\/li>\n\n\n\n<li>There will be low vitamin D<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading page-header\" id=\"obesity\">Obesity and After Bariatric Surgery<\/h2>\n\n\n\n<p>Research has begun to show a relationship between BMI and vitamin D deficiency. A study done on 2,187 overweight and obese subjects, found that those with a <a href=\"https:\/\/www.drrpadmakumar.com\/body-mass-index.php\">BMI <\/a>above 40 had 18% lower serum vitamin D levels than those with a BMI under 40. Some possible reasons for this are lower intakes of vitamin D , less exposure to sunlight (uv) radiation and a higher distribution volume of vitamin D . Even with exposure to sunlight, there remains a risk for deficiency.<\/p>\n\n\n\n<p>Morbid obese patients have a higher incidence of high PTH and low vitamin D even before surgery compared with normal individuals.<\/p>\n\n\n\n<p>In gastric bypass: low calcium absorption due to bypassed duodenum and jejunum may be the cause.<\/p>\n\n\n\n<p>In <a href=\"https:\/\/www.drrpadmakumar.com\/blog\/laparoscopic-sleeve-gastrectomy-weight-loss\/\">sleeve gastrectomy<\/a> the vitamin D and calcium level are maintained within normal limits compared to <a href=\"https:\/\/www.drrpadmakumar.com\/blog\/bypass-procedures-for-weight-loss\/\">bypass surgery<\/a>.<\/p>\n\n\n\n<div class=\"row row-cols-1 g-4 bg-lightblue mt-2 mb-3 pb-2\">\n    <div class=\"col\">\n        <div class=\"card h-100 shadow cardhover\">\n            <div class=\"card-body\">\n                <h5 class=\"card-title\">Bariatric Surgery<\/h5>\n                <img decoding=\"async\" data-src=\"https:\/\/www.drrpadmakumar.com\/blog\/wp-content\/uploads\/2022\/06\/bariatric-surgery-thumbnail-1.jpg\"\n                    alt=\"Bariatric Surgery\" class=\"float-end ms-2 img-thumbnail lazyload\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 100px; --smush-placeholder-aspect-ratio: 100\/100;\">\n                <p class=\"card-text\">Bariatric Surgery deals with the study of obesity, the causes, prevention and\n                    treatment of obesity. Different weight loss procedures are Laparoscopic Sleeve Gastrectomy,\n                    Roux-en-Y Gastric Bypass, Mini Gastric Bypass, Laparoscopic Gastroplasty. Intragastric Balloon Placement is a non-surgical weight loss procedure.\n                <\/p>\n\n                <div class=\"text-start\">\n                    <a href=\"\/blog\/bariatric-surgery\/\" class=\"btn btn-sm btn-outline-secondary\">Bariatric Surgery<\/a>\n                    <a href=\"\/blog\/laparoscopic-sleeve-gastrectomy-weight-loss\/\"\n                        class=\"btn btn-sm btn-outline-secondary mt-1\">Sleeve Gastrectomy<\/a>\n                    <a href=\"\/blog\/bypass-procedures-for-weight-loss\/\"\n                        class=\"btn btn-sm btn-outline-secondary mt-1\">Roux-en-Y Gastric Bypass<\/a>\n                    <a href=\"\/blog\/laparoscopic-gastroplasty\/\"\n                        class=\"btn btn-sm btn-outline-secondary mt-1\">Gastroplasty<\/a>\n                    <a href=\"\/blog\/intragastric-balloon-weight-loss\/\"\n                        class=\"btn btn-sm btn-outline-secondary mt-1\">Intragastric Balloon Placement<\/a>\n                <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading page-header\" id=\"gallbladder-disease\">Gallbladder Disease and Vitamin D Deficiency<\/h2>\n\n\n\n<p>Low vitamin D may cause gallbladder stone formation<\/p>\n\n\n\n<p>Gall bladder removal may reduce vitamin D and magnesium levels. This may be due to reduced absorption of fat soluble vitamins (D, E, A and K).<\/p>\n\n\n\n<p>People with compromised liver or digestive function are often vitamin D deficient. Exposure of skin to the sun\u2019s <a href=\"https:\/\/en.wikipedia.org\/wiki\/Ultraviolet\" target=\"_blank\" rel=\"noreferrer noopener\">UVB<\/a> rays enables body to manufacture vitamin D. However, this process occurs in the liver and kidneys. Here people with a sluggish liver often do not manufacture vitamin D adequately.<\/p>\n\n\n\n<div class=\"row row-cols-1 g-4 bg-lightblue mt-2 mb-3 pb-2\">\n    <div class=\"col\">\n        <div class=\"card h-100 shadow cardhover\">\n            <div class=\"card-body\">\n                <h5 class=\"card-title\">Gallbladder Surgery<\/h5>\n                <img decoding=\"async\" data-src=\"https:\/\/www.drrpadmakumar.com\/blog\/wp-content\/uploads\/2022\/07\/gallbladder-icon.jpg\"\n                    alt=\"Gallbladder Surgery\" class=\"float-end ms-2 img-thumbnail lazyload\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 100px; --smush-placeholder-aspect-ratio: 100\/100;\">\n                <p class=\"card-text\">The gallbladder is an organ that helps in the digestion process. Gallstones is a\n                    common cause of Gallbladder disease. Laparoscopic Cholecystectomy is a procedure performed to remove\n                    the gallbladder from the body<\/p>\n                <a href=\"\/blog\/laparoscopic-cholecystectomy\/\" class=\"btn btn-sm btn-outline-secondary\">Laparoscopic Cholecystectomy<\/a>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading page-header\" id=\"treatment\">Treatment<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Sun rays exposure<\/li>\n\n\n\n<li>Increased oral supplements<\/li>\n\n\n\n<li>When the blood level of vitamin D is below 30 ng\/ml, a minimum of 1,000 IU\/day will be needed for children and 1,500 to 2,000 IU\/day of vitamin D3 for adults.<\/li>\n\n\n\n<li>Another rule of thumb is for every 1 ng\/ml increase in blood level one need is an additional 100IU\/day.<\/li>\n\n\n\n<li>In obese patients , with malabsorbtion syndromes and patients on medications affecting vitamin D metabolism, it is advised to have a higher dose (two to three times higher , atleast 6,000-10,000IU\/day) of vitamin D to treat deficiency to maintain a 25(OH)D level above 30ng\/ml, followed by maintenance therapy of 3,000-6,000IU\/day.<\/li>\n\n\n\n<li>After parathyroid removal , may be wise to have a concomitant replacement of vitamin D with calcitriol (0.25-1mcg\/day). Dependence on calcium supplementation for more than 6 months shows permanent hypoparathyroidism; which will necessitate continued use of such medications.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Vitamin D deficiency in a Surgeon\u2019s perspective is relevant in Author: Dr R Padmakumar et al. Contents Introduction: Vitamin D is a fat soluble vitamin and produced by skin (from cholesterol) when exposed to ultraviolet B radiation (\u201csunshine vitamin\u201d) and also obtained from dietary sources, including supplements. Most important components, vitamin D3 (cholecalciferol) comes from [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2043,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[55],"class_list":["post-895","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-literature","tag-publications"],"_links":{"self":[{"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/posts\/895","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/comments?post=895"}],"version-history":[{"count":58,"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/posts\/895\/revisions"}],"predecessor-version":[{"id":3784,"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/posts\/895\/revisions\/3784"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/media\/2043"}],"wp:attachment":[{"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/media?parent=895"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/categories?post=895"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.drrpadmakumar.com\/blog\/wp-json\/wp\/v2\/tags?post=895"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}